Millions of pounds will once again be raised to help tackle poverty, domestic abuse and racial inequality, as well as supporting front line workers.
It also gives us a chance to look back on the wonderful ways you have raised money in South Tyneside in the past.
Were you one of the South Tyneside College students pictured on roller skates or the Sainsbury’s staff having fun in 2007?
Maybe you can spot someone you know at Beach Hill Nursery or Westoe Infants School.
We have all this and more for you to enjoy. Take a look and re-live the Red Nose memories.
1. Doing it in style
It's Red Nose Day in 2005 and these Parsons staff were having a great time. Remember this? Photo: TC
2. Bouncing back to 2013
A Comic Relief yoga session at the Phoenix Centre 8 years ago. Claire Modrate (Family Support Worker) (left) and Ivy-Rose Crowe look on as Sarah Noble and Isle Gabriella Jamieson, Sarah-Jayne Larking and Harrison Martin, Andrea and Lola Atkinson take part. Photo: FRANK REID
3. So colourful at Golden Flatts
Red Nose Day at Golden Flatts School in 2005. Do you recognise the pupils having fun? Photo: TC
4. Cleaning up in 2009
A sponsored car wash at Sainsbury's in Hartlepool in 2009. Did you take part? Photo: FLR