Nexus, which owns and manages Metro, is closing Metro Central Station from 8pm this Thursday (March 10) until the end of Metro services on Sunday.
The three day closure is needed to replace essential electrical distribution equipment which provides the station with its power supply, including lighting and fire safety.
The work is part of a £6million modernisation programme for the service. Members of the public will be able to gain access to the station as normal from 5am on Monday (March 14).
Metro services will still run through the station when it is closed, but the trains will not stop. Passengers are being advised to leave the Metro at Monument or Haymarket instead.
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Additional staff will be on duty at Central Station to assist passengers wishing to use the Metro, and also those arriving at Central Station from mainline trains.
Raymond Johnstone, director of Rail and Infrastructure for Nexus, said: "I'm sorry for the inconvenience caused by closing Central Metro station for three days.
“The station has to be shut so that we can carry out important electrical works. It’s a huge amount of work which is a bit like rewiring an entire house, only a lot more complex. This can only be done safely during a full station closure.
“There will be extra staff on duty to assist passengers.”