After taking seven points from a possible nine during their previous three games, there is a quiet sense of optimism that the Magpies could come away with something from Anfield – a ground they haven’t won on since April 1994.
That said, Jurgen Klopp’s side, who have lost at home to Fulham, Brighton and Burnley this season, head into the fixture with everything to play for in their race to claim a Champions League spot.
Klopp confirmed in his pre-match press conference that midfielder Curtis Jones is back in contention, however Nathaniel Phillips, Jordan Henderson, Joel Matip, Joe Gomez, Virgil van Dijk and Divock Origi remain out.
Nevertheless, the German has plenty of options to select from as Newcastle eye a shock result to significantly boost their Premier League survival hopes.
Take a look through our gallery as we predict the Liverpool starting XI to face Bruce’s side:
1. Alisson
Liverpool’s number one. The Brazillian always gets the nod over Adrian when fit and available. Photo: Clive Brunskill
2. Trent Alexander-Arnold
The right-back has responded well after being left out of Gareth Southgate’s England squad last month with two assists and a goal in his last three appearances. Photo: Laurence Griffiths
3. Fabinho
Jurgen Klopp has had to contend with a number of defensive injuries this season, with Fabinho often called upon as cover at the heart of the defence. Photo: Pool
4. Ozan Kabak
The Turkish international looked set to join Newcastle in January before Liverpool swooped in on deadline day. Photo: Pool