The striker came off the bench for the final 25 minutes of the match as Newcastle fell to a 5-0 defeat at the Etihad Stadium.
It was the first time Wilson had featured for United since being forced off with a serious calf injury against Manchester United in December.
While Wilson admitted it was ‘so nice’ to get back out on the pitch, a one-on-one chance he had that was stopped by Ederson has haunted him ever since.
“It was nice, it was so nice,” Wilson said. “City away is never an easy one to come back to but this is the Premier League and no game is easy.
“I came on a bit later in the game and we were 3-0 down at the time and it was all just about helping the team get back into the game.
“I tried to do that, should have done that, I had an opportunity to score which is the most frustrating thing when you’ve been out for so long and you come back and then you have a one-on-one, it’s something you’ve worked on throughout your rehab for so long that technically, you know you can put it in and nine times out of 10 you score.
“I’m a matchday finisher and by my standards I was thoroughly disappointed. It’s something that has haunted me for the last couple of days but that’s also something that when you’re fit and playing you’re just like boom, boom, boom, boom, you’ve got another opportunity to do it.
“But for me, because there’s only two games left now, it’s like time is running out and I’m trying to make up for lost time. Any opportunity like that, I’m hard on myself, I have to score that.
“The main thing is that I’ve come back having chances and opportunities to score and as a striker that is the most important thing.”
Check out the latest Premier League transfer speculation below...
1. Man United among front-runners for Osimhen
Manchester United are among the front-runners to sign Napoli striker Victor Osimhen, with the striker valued at around £85m. (Sport Mediaset)
2. West Ham drop out of Tarkowski race
West Ham are set to drop their interest in James Tarkowski as they expect him to join Newcastle this summer. The Toon Army are now in ‘pole position’ for the defender. (Mirror)
3. Hammers could look for permanent Areola deal
West Ham could be ready to sign Alphonse Areola permanently by triggering an £8.5m option in his loan deal. (L’Equipe)
4. Lawrence attracting attention
Fulham, Burnley, and Norwich City are among the clubs interested in Derby County winger Tom Lawrence following the Rams’ relegation from the Championship. (Daily Mail)