A Miguel Almiron brace and goals from Callum Wilson and Sean Longstaff saw Eddie Howe’s side cruise to victory despite Bobby De Cordova-Reid’s late consolation.
Callum Wilson gave Newcastle the lead shortly after Nathaniel Chalobah’s early red card for Fulham.
Miguel Almiron then doubled The Magpies’ advantage in the first half with a stunning volley in the left side of the goal.
Just before the break, Sean Longstaff pounced on a Bernd Leno save from Sven Botman to make it 3-0 to the visitors.
Almiron then grabbed his second of the afternoon after turning in Joe Willock’s cross from close range.
Newcastle looked to be heading towards a 4-0 win when Fulham pulled back a consolation goal in the closing stages through Bobby De Cordova-Reid to make it 4-1.
9. Miguel Almiron - 9
A sensational finish doubled Newcastle’s lead inside the first half. Scored his second of the game with a far simpler finish in the second half. Thought he’d scored a hat-trick only to be denied by the offside flag. Couldn’t ask for much more from a player whose end product has been questioned at times. | Getty Images
10. Jacob Murphy - 6
Seemed to have the freedom of Craven Cottage at times as he got into some dangerous areas with plenty of space but couldn’t quite find the net or the killer pass. A solid first start of the season. | Getty Images
11. Callum Wilson - 8
Had a great opportunity to score inside the opening five minutes but the chance went begging. Didn’t need a second opportunity shortly after as he turned in Joe Willock’s header on the line. A good return to the side. | Getty Images
12. Elliot Anderson - 7
On for Guimaraes 59: Had a good chance to score as his effort deflected wide. Got into some good positions but was often thwarted by the Fulham defence. | AFP via Getty Images