Millions of pounds will once again be raised to help tackle poverty, domestic abuse and racial inequality, as well as supporting front line workers.
It also gives us a chance to look back on the wonderful ways you have raised money in South Tyneside in the past.
Were you one of the South Tyneside College students pictured on roller skates or the Sainsbury’s staff having fun in 2007?
Maybe you can spot someone you know at Beach Hill Nursery or Westoe Infants School.
We have all this and more for you to enjoy. Take a look and re-live the Red Nose memories.
5. Fun times at Holy Trinity
Seaton Carew Holy Trinity Junior School pupils Alfie Sutheran and Eve Menzies showed their support for Red Nose Day in 2013. Photo: FRANK REID
6. Now that's a big red nose!
Throston Primary School pupils created a giant red nose in the playground in 2009. Did you take part? Photo: TC
7. Full of beans in 2005
A bath in beans at Asda in Peterlee in 2005. Remember this? Photo: MH
8. On the ball at St Bega's
The whole netball team at St Bega's School took part in the Red Nose Day fun in 2003. Can you spot someone you know? Photo: LH