Martin Dubravka handed Newcastle debut against Man United
Dubravka, signed on loan from Sparta Prague last month, has been handed a start against Manchester United.
Rafa Benitez's side take on Jose Mourinho's side looking for their first home win since October 21.
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Hide AdFlorian Lejeune also comes into the starting XI, but on-loan striker Islam Slimani is not involved, having failed to prove his fitness in time.
NEWCASTLE UNITED: Dubravka; Yedlin, Lascelles, Lejeune, Dummett; Shelvey, Diame; Ritchie, Perez, Kenedy; Gayle. Subs: Darlow, Manquillo, Hayden, Merino, Atsu, Murphy, Joselu.
MANCHESTER UNITED: De Gea, Valencia, Jones, Smalling, Young, Matic, Pogba, Martial, Lingard, Sanchez, Lukaku. Subs: Romero, LIndelof, Rojo, Mata, Carrick, Shaw, McTominay.