Benitez's side take on Tottenham Hotspur tonight (8pm kick-off) in the club's penultimate game of the season.
And Benitez has recalled Matt Ritchie and DeAndre Yedlin to his starting XI.
Newcastle are 10th in Premier League table and in need of a win to secure a top-half finish.
Fourth-placed Tottenham, meanwhile, are under pressure from Chelsea, who visit St James's Park on Sunday.
Five United players – Matt Ritchie, Mohamed Diame, Jonjo Shelvey, Dwight Gayle and Martin Dubravka – have played at Wembley with previous clubs or their countries, while Javier Manquillo was an unused substitute with Liverpool.
Meanwhile, former Newcastle midfielder Moussa Sissoko is in Tottenham's starting XI.
NEWCASTLE UNITED: Dubravka; Yedlin, Lascelles, Lejeune, Dummett; Shelvey, Diame; Ritchie, Perez, Kenedy; Gayle. Subs: Darlow, Manquillo, Haidara, Hayden, Murphy, Merino, Joselu.
TOTTENHAM HOTSPUR: Lloris, Trippier, Sanchez, Vertonghen, Davies, Wanyama, Sissoko, Eriksen, Dele, Son, Kane. Subs: Vorm, Rose, Alderweireld, Lamela, Llorente, Foyth, Moura.