The Red Devils have had a rough start to the new Premier League season with a controversial last-minute win at Brighton and two defeats under their belt so far.
Before the international break, Ole Gunnar Solskjaer's side were humiliated by a 6-1 home defeat to Tottenham Hotspur.
A red card for Anthony Martial rules him out of the match while Harry Maguire is a doubt with a knock as Solskjaer faces a decision whether to take him out of the firing line.
Scroll down and click through the pages to see our predicted Manchester United line-up for today's match...
1. GK - David de Gea
His starting position isn't as secure as it has been in previous seasons with Dean Henderson breathing down his neck. Photo: Alex Livesey
2. LB - Luke Shaw
Set to make his 100th Premier League appearance for The Red Devils, six years after joining from Southampton. Photo: Ash Donelon
3. CB - Victor Lindelof
Could return to the starting XI after losing his place for the Spurs defeat. Photo: RICHARD HEATHCOTE
4. CB - Harry Maguire
The Man United skipper has came under fire so far this season but could be handed another chance at St. James's Park tonight. Photo: Pool