The Red Devils have had a rough start to the new Premier League season with a controversial last-minute win at Brighton and two defeats under their belt so far.
Before the international break, Ole Gunnar Solskjaer's side were humiliated by a 6-1 home defeat to Tottenham Hotspur.
A red card for Anthony Martial rules him out of the match while Harry Maguire is a doubt with a knock as Solskjaer faces a decision whether to take him out of the firing line.
Scroll down and click through the pages to see our predicted Manchester United line-up for today's match...
. MANCHESTER, ENGLAND - OCTOBER 04: Harry Maguire of Manchester United looks dejected during the Premier League match between Manchester United and Tottenham Hotspur at Old Trafford on October 04, 2020 in Manchester, England. Sporting stadiums around the UK remain under strict restrictions due to the Coronavirus Pandemic as Government social distancing laws prohibit fans inside venues resulting in games being played behind closed doors. (Photo by Oli Scarff - Pool/Getty Images)
Harry Maguire of Manchester United looks dejected during the Premier League match between Manchester United and Tottenham Hotspur at Old Trafford on October 04, 2020( Photo by Oli Scarff - Pool/Getty Images) Photo: Pool
. GK - David de Gea
His starting position isn't as secure as it has been in previous seasons with Dean Henderson breathing down his neck. Photo: Alex Livesey
. LB - Luke Shaw
Set to make his 100th Premier League appearance for The Red Devils, six years after joining from Southampton. Photo: Ash Donelon
1. GK - David de Gea
His starting position isn't as secure as it has been in previous seasons with Dean Henderson breathing down his neck. Photo: Alex Livesey
2. LB - Luke Shaw
Set to make his 100th Premier League appearance for The Red Devils, six years after joining from Southampton. Photo: Ash Donelon
3. CB - Victor Lindelof
Could return to the starting XI after losing his place for the Spurs defeat. Photo: RICHARD HEATHCOTE
4. CB - Harry Maguire
The Man United skipper has came under fire so far this season but could be handed another chance at St. James's Park tonight. Photo: Pool