While that may sound odd, given the stature of their opponents, this is a Man United team in transition under Ole Gunnar Solskjaer.
The Red Devils are no longer the force they once were. Solskjaer has injury and selection problems, with Aaron Wan Bissaka, Luke Shaw, Anthony Martial and Paul Pogba all set to miss out, and they have failed to win away from home in their last 10 outings.
They were held by AZ Alkmaar on Thursday night and drew 1-1 with Arsenal in their last Premier League match. We take a look at SEVEN key tactical areas that could see Newcastle pick up a much-needed three points.
1. Ashey Young is a weak link
Pace on the counter attack could exploit the gaps Young leaves | JPIMedia Photo: Duncan Jackson
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2. Support the striker
Can the midfielders break the lines to put pressure on Man United's defence? | JPIMedia Photo: Duncan Jackson
3. Overlaps on the right flank
Could DeAndre Yedlin have a key role to play? | JPIMedia Photo: Duncan Jackson
4. Defensive reshuffle
The full-backs were all at sea against Leicester. | JPIMedia Photo: Duncan Jackson