Newcastle visit Liverpool on Thursday, then they host Manchester City and Manchester United before making another trip to Merseyside to face Everton before the end of 2021.
With such a hectic schedule to come, it would come as no surprise to see Howe rotate his squad to give players time to rest and to reduce injuries.
But how much as he rotated so far during his brief time as manager? And can we use this to predict how different each Newcastle United starting XI will look on a game by game basis over Christmas?
Here, using data provided by BettingExpert, we have listed how many changes, on average, each Premier League manager makes to their starting XI for each game:
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13. Steven Gerrard - 2
As Steven Gerrard begins to find his feet at Villa Park, it’s only natural that he is yet to nail down his starting XI. Photo: Shaun Botterill
14. Ralph Hasenhuttl - 2.19
Saints have had injury problems themselves and their inconsistent form is possibly down to their inability to pick a consistent starting side. Photo: Mike Hewitt
15. Eddie Howe - 2.2
Howe has a monumental job on his hands to keep Newcastle United in the Premier League and it’s clear, from the amount of changes he has made so far, that he is still to settle on a preferred starting team. Photo: Stu Forster
16. Jurgen Klopp - 2.25
As Liverpool balance the demands of progressing far in the Champions League and battling it out at the top of Premier League, Klopp has rotated his side in order to keep them fresh. Photo: Clive Brunskill