The Magpies could hand debuts a number of their new stars, including midfielder Bruno Guimarães and centre-back Dan Burn.
One deal Newcastle failed to get over the line was a loan move for Man Utd midfielder Jesse Lingard, who ended up staying at Old Trafford.
Ex-Magpies man Alan Smith gave his verdict on the failed move, and contended: “I’m sure that Jesse would want to stay at [Manchester] United and force his way into the team, or at least into the squad every week.
“For any player, and I’ve been there myself, leaving Man United is tough because of the stature of the club, wherever you go you will always feel like you’re dropping down.
“I think he surprised a lot of people when he went to West Ham, just how good he was. He surprised people with his performances, and I think that tells you how difficult and exactly what the demands at Manchester United are.
"He went there and he set the world alight at West Ham and came back to Man United hoping to bridge that gap and get into the team, but it’s not quite happened for him.
“We don’t know the conversation that has happened with the coach, but only Jesse himself will himself know whether he really wanted to leave, because there’s a big difference between someone saying you can leave and the player actually wanting to leave.”
Take a look at all the latest stories from the Premier League, as the reaction to the transfer window and build-up to the top tier's return continue:
5. Villa to come back for Bissouma
Aston Villa have been tipped to reignite their interest in Brighton's £50m-rated midfielder Yves Bissouma this summer. Former Villa man Alan Hutton has claimed that the side could well return for the player, after being put off by his asking price last month. (Football Insider) Photo: Mike Hewitt
6. Hodgson's surprise Hornets admission
Watford's new manager Roy Hodgson has revealed he "no input whatsoever" into the club's transfer activity since joining the club. He's said he's focused on finding out "how best to use" the players at his disposal instead, and won't have a say in the players who leave. (BBC Sport) Photo: Pool
7. Hamann backs Weghorst to shine
Ex-Liverpool star Didi Hamann has backed Burnley's new striker Wout Weghorst to be a success at his new club. The German branded the £12m man "prolific", citing his impressing goalscoring form with former club VfL Wolfsburg. (Sky Sports News) Photo: Thomas Eisenhuth
8. Whites and Villa knocked back by Hammers
Leeds United are said to have made a deadline day move to bring in West Ham United goalkeeper Darren Randolph on loan, but the Hammers wouldn't allow the stopper to leave. Aston Villa were also said to be keen on the Republic of Ireland international. (The Athletic) Photo: Alex Davidson