The Magpies went into the international break in reasonable spirits, after their 1-1 draw with Southampton saw them pick up their first points of the 2021/22 campaign.
Writing his weekly predictions piece for BBC Sport, pundit and broadcaster Mark Lawrenson gave his verdict on Newcastle's trip to take on the Red Devils, and tipped the hosts to pick up a comfortable 3-0 win.
Expanding on his choice, the 64-year-old wrote: “Newcastle badly need a win, but Old Trafford, on the day Ronaldo makes his return, is not the time or place for them to get it.
“There is no doubt Ronaldo's arrival has improved Manchester United. In terms of what he brings to the team, well, he won't be chasing full-backs down, will he?
It will be a case of 'you stay up there, we will get the ball to you'. It is pretty basic, but why wouldn't you do that with Ronaldo in your side, when he is so good in the air?
He concluded: “If he gets the service you'd expect him to from the players behind him, he is going to score plenty - and he'll probably be taking every penalty, free-kick and even the throw-ins and goal-kicks too.”
Meanwhile, Lawro's prediction opponent for the week, The Vaccines frontman and Man Utd fan Justin Young, backed his team to win 3-0.
We’ve gathered the best of today's Premier League speculation below…

5. Leeds still in O'Brien talks
Leeds United are still in talks over a potential move for Huddersfield Town midfielder Lewis O’Brien in January deal, with the player 'desperate to join' the Whites. (Football Insider) (Photo by George Wood/Getty Images) Photo: George Wood

6. Potter in Gunners' sights
Graham Potter and Thomas Frank are emerging as potential head coaching candidates for Arsenal if, and when, they decide to move on from Mikel Arteta. (TEAMtalk) (Photo by Steve Bardens/Getty Images) Photo: Steve Bardens

7. Leeds made Jones approach
Leeds United made an ambitious move to try and sign Liverpool midfielder Curtis Jones on loan, but were denied this summer. (Goal) (Photo by Lewis Storey/Getty Images) Photo: Lewis Storey

8. Diakhaby set to leave
Valencia “plan to sell” Mouctar Diakhaby during the upcoming winter transfer window. Newcastle United and Leicester City have both been linked. (Deporte Valenciano) (Photo by Aitor Alcalde/Getty Images) Photo: Aitor Alcalde

