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Premier League football is back following the second international break of the season and Newcastle host a Palace side that sit just one place and one point below them in the table.
If the Magpies are able to avoid defeat against the Eagles, they will extend their current unbeaten run to eight games in all competitions.
However, Eddie Howe does have one or two selection headaches to contend with ahead of the game - although they pale in comparison to his opposite number.
Palace are in the middle of a major injury crisis and whilst the international period has alleviated a little bit of the stress on the medical department, they still have a fair few injury problems to deal with.
Here, we take a look at the latest injury news from both camps:
13. Joe Willock - out
Willock still remains sidelined with an achilles injury but he is edging closer to a potential return to action in the not too distant future. | Getty Images
14. Alexander Isak - doubt
Eddie Howe admitted that Isak hadn’t trained during the international break and that they would make a late call on his fitness. With Callum Wilson seemingly back to fitness, it’s unlikely that Isak will be risked against Palace. | AFP via Getty Images
15. Lewis Miley - out
Miley is suffering from glandular fever and will not feature against Hodgson’s side. The 17-year-old is yet to feature in the Premier League this season, with his only taste of first-team action coming against Manchester City in the Carabao Cup. | Getty Images
16. Sven Botman - doubt
Botman is still suffering with a knee injury and remains a doubt for Saturday’s match. With a hectic schedule to come, it’s unlikely that he will be risked if not at full fitness. | AFP via Getty Images