Eddie Howe’s side would go above their opponents with a win on Sunday, but to do that, they will have to win at a venue they have taken three points from just once in Premier League history.
Last weekend’s win over Brentford moved Newcastle temporarily into fifth after a very good start to the campaign with goals from Miguel Almiron, Jacob Murphy and Bruno Guimaraes enough for the win at St James’s Park.
Following that win, Howe has a number of selection issues to deal with and following such a comprehensive win - will the head coach make any major changes to his starting side?
Here, we take a look at the starting XI Howe could name for Newcastle United’s trip to face Manchester United.
Do you agree with our selection? Follow us on social media and let us know your thoughts there.

9. RW: Miguel Almiron
Almiron is on fire at the minute and is possibly one of the first names on Howe’s team sheet, although that is a very crowded field right now. His workrate will be needed to help protect Trippier against players like Antony and Marcus Rashford. Photo: Ian MacNicol

10. ST: Callum Wilson
Newcastle have netted nine times in their last two outings and surprisingly, Wilson has scored just one of them. Despite failing to find the back of the net last weekend, Wilson remains Newcastle’s main man up-front and will be seeking revenge against Manchester United after his season was halted last year following injury against Sunday’s opponents. Photo: Ian MacNicol

11. LW: Allan Saint-Maximin
Saint-Maximin is slowly recovering from injury and Howe has been reluctant to throw the Frenchman into his starting side, however, at Old Trafford, the winger could be afforded the space to create carnage in the Manchester United back line, particularly when Newcastle get given the opportunity to counter attack. Photo: Stu Forster

