Newcastle United have been dealt a fresh fitness blow ahead of Saturday evening's match against Arsenal at the Emirates Stadium.
Martin Dubravka has not travelled with the squad for the match due to illness. A tweet posted by the club read: "Martin Dúbravka misses out through illness this evening."
The Magpies' latest fitness blow sees Dubravka drop out of the side to be replaced by Loris Karius for his first Premier League appearance for the club. Karius has only played one competitive match for Newcastle previously, a 2-0 defeat to Manchester United in the Carabao Cup final almost exactly a year ago.
A further update on Dubravka's situation will be provided by Eddie Howe after the match with Newcastle travelling to face Blackburn Rovers in the FA Cup fifth round on Tuesday night.
United have seven players ruled out of the match against Arsenal due to illness, injury or suspension but have just welcomed back Alexander Isak and Joe Willock from injury issues. Isak had been out for the last three matches with a groin issue while Willock hasn't featured for Newcastle since November due to a recurring Achilles problem.
Newcastle have suffered recent blows to the likes of Callum Wilson and Joelinton, who are both out until the latter part of the season.
1. Matt Targett (achilles)
Targett has been missing since picking up a hamstring injury against Man Utd back in November. He has featured on the bench in their last couple of outings before dropping out v West Ham and Everton in what is understood to be a minor setback in his recovery. Expected return: Tottenham Hotspur (H) - 13/04 | Getty Images
2. Kieran Trippier (calf)
Trippier was forced off during the 3-0 win over Wolves with a calf injury. He has since been ruled out for over a month. Set for another couple of weeks out at least. Expected return: Crystal Palace (A) - 24/04 | Getty Images
3. Nick Pope (shoulder)
Nick Pope dislocated his shoulder against Manchester United in December and required surgery. Eddie Howe has said the goalkeeper is still a number of weeks away and isn't expected back until 'late April'. Expected return: Sheffield United (H) - 27/04 | Getty Images
4. Tino Livramento (ankle)
Livramento picked up a twisted ankle injury at Chelsea which ruled him out for the Manchester City trip. He returned against West Ham United before suffering another ankle injury which will keep him out for another couple of weeks. Expected return: Burnley (A) - 04/05 | Getty Images