The 3-2 FA Cup fifth round win at West Brom on Tuesday was met by six changes from the previous top-flight encounter with Burnley. We’re expecting Steve Bruce to rotate his squad for the visit of St Mary’s, but who will make the cut? Scroll and click through the pages as we predict Bruce's XI:
1. GK: Martin Dubravka
Has played every Premier League minute for Newcastle since joining from Sparta Prague in January 2018. In for Karl Darlow. | Getty Images Photo: Alex Livesey
2. RB: DeAndre Yedlin
Bruce confirmed Javier Manquillo is feeling sore in the build-up to Saturday’s game - so could that mean a recall for Yedlin or possibly field Valentino Lazaro at right-back? | Getty Images Photo: Catherine Ivill
3. CB: Federico Fernandez
Didn’t play at the Hawthorns in midweek but has started Newcastle’s last 19 Premier League fixtures. | Getty Images Photo: Nigel Roddis
4. CB: Jamaal Lascelles
Has played and captained every game since his return from injury in the 1-0 win over Chelsea at St James’s Park on January 18. | Getty Images Photo: Mark Runnacles