Newcastle have no representatives in the current Three Lions squad despite calls for in-form defenders Dan Burn and Matt Targett to be considered.
And United’s Swiss defender Fabian Schar has had to withdraw from the match due to a groin issue.
Kieran Trippier is an England regular who has played a key role in the last two major tournaments but his current metatarsal injury ruled him out of a call-up.
But with the 2022 FIFA World Cup in Qatar less than eight months away, how many current Newcastle players can we expect to be part of Gareth Southgate’s 23-man squad?
United have several players who are potentially available for selection. Of Newcastle’s 14 senior players eligible to play for England, only Trippier, Callum Wilson and Jonjo Shelvey have registered an international cap.
Here are their chances of going to Qatar…
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Kieran Trippier is an England regular who has played a key role in the last two major tournaments but his current metatarsal injury ruled him out of a call-up.
5. Joe Willock - 11/1
A 22-year-old English midfielder with the ability to pop up with a goal - Joe Willock certainly seems like an ideal fit into the England set-up should he be able to build on his improving form. But if scoring in seven consecutive matches from midfield last season wasn't enough to get him in England's Euro 2020 squad, what will it take for him to get the nod for Qatar? Photo: GEOFF CADDICK
Shelvey has been in good form for Newcastle under Eddie Howe which have started some murmurs of a potential England recall. The 30-year-old has played six times for his country but his last appearance came in 2015, before he joined The Magpies. He was in fine form at the back end of the 2017-18 season but didn't get a look in for the 2018 World Cup squad so it would take something special for him to be in with a reasonable shout of going to Qatar. Photo: Mike Hewitt
The 24-year-old has seen his playtime limited since the turn of the year but has still been able to put in a shift when called upon. He is yet to be recognised on the international stage. It would be a huge surprise to see him handed an England call-up this year given the abundance of young midfielders at Gareth Southgate's disposal at the moment. Photo: Stu Forster
Matt Targett was unfortunate not to be called-up to the latest England squad given his form and the Three Lions' options at left-back. The 20/1 odds make him seem like a real outsider but he seems a far more realistic option than most current Newcastle players. He's still only 26 and has progressed through the system at England, being capped at Under-19, Under-20 and Under-21 level. All that is remaining is that senior cap. Photo: Dan Mullan