With Callum Wilson already out of action, and with the gap between themselves and the relegation zone at just three points, the news that Allan Saint-Maximin and Miguel Almiron are both set to be sidelined until at April could be a hammer blow for the Magpies’ survival hopes.
Aside from that trio, Jeff Hendrick is the only Toon player to have scored more than one goal in the league this season.
Currently, Newcastle have seven players out injured – the joint-fourth-highest tally in the Premier League – but how have their fared over the course of the entire season compared to their top flight rivals?
We’ve taken a look at the total number of matches that players at each Premier League club have missed this term to determine who’s really had the worst luck in 2020/21…
*All data courtesy of Transfermarkt.
17. Southampton
Total matches: 115 Players injured: 17 Longest absence: Sam McQueen (Photo by Mike Egerton - Pool/Getty Images) Photo: Pool
18. Newcastle United
Total matches missed: 123 Players injured: 18 Longest absence: Paul Dummett (Photo by Stu Forster/Getty Images) Photo: Stu Forster
19. Liverpool
Total matches missed: 151 Players injured: 17 Longest absence: Virgil van Dijk (Photo by Phil Noble - Pool/Getty Images) Photo: Pool
20. Crystal Palace
Total matches played: 165 Players injured: 20 Longest absence: Nathan Ferguson (Photo by Mike Hewitt/Getty Images) Photo: Mike Hewitt