The winger started Saturday’s goalless draw against Burnley at St James’s Park from the bench.
Saint-Maximin had felt his hamstring ahead of the Premier League fixture.
However, the 22-year-old could start against West Bromwich Albion in tomorrow’s night’s fifth-round FA Cup tie.
Head coach Steve Bruce said: “I hope so. He was a bit sore, and we're always a bit wary the way he plays.”