Eddie Howe’s side have a nine-point cushion to Watford who currently occupy the last place in the relegation zone.
But up next for the Magpies is a tricky trip to face Antonio Conte’s Tottenham Hotspur.
The break has allowed Newcastle to refresh themselves after a gruelling schedule - but will that have an effect on their Premier League run-in?
Safety is by no means assured for Howe and his team, however, a couple of positive results in the next few weeks, starting in the capital, could have a dramatic effect on the relegation picture.
Here, courtesy of FiveThirtyEight, we take a look at the latest supercomputer predictions and how that rates Newcastle United’s chances of survival this season and how the Premier League table will look when it comes to its conclusion on May 22.
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1. Manchester City
Predicted finish: 1st - Predicted points: 91 (+64 GD) - Chances of winning the Premier League: 62% - Chances of defeating Burnley this weekend: 77% Photo: Michael Regan
2. Liverpool
Predicted finish: 2nd - Predicted points: 89 (+68 GD) - Chances of winning the Premier League: 38% - Chances of defeating Watford this weekend: 87% Photo: Justin Setterfield
3. Chelsea
Predicted finish: 3rd - Predicted points: 80 (+48 GD) - Chances of winning the Premier League: 99% - Chances of defeating Brentford this weekend: 68% Photo: Justin Setterfield
4. Arsenal
Predicted finish: 4th - Predicted points: 71 (+18 GD) - Chances of qualifying for the Champions League: 67% - Chances of defeating Crystal Palace on Monday: 50% Photo: Stuart MacFarlane