DeAndre Yedlin, Jetro Willems, Jonjo Shelvey, Fabian Schar and Javier Manquillo picked up injuries in the Leicester defeat – joining Matt Ritchie, Jamaal Lascelles, Allan Saint-Maximin, Paul Dummett and Ciaran Clark on the treatment table. Some players could return but Bruce has been left a little light. Click through the pages to see our predicted starting 11:
1. RB: Jamie Sterry
United are enduring an injury crisis in the full-back areas with DeAndre Yedlin, Javier Manquillo, Paul Dummett and Jetro Willems all doubtful for Saturday. Photo: Ian MacNicol
2. CB: Isaac Hayden
Bruce spoke about wanting to give Florian Lejeune a rest after playing three consecutive games so soon since returning from an ACL injury. Maybe Rochdale is the chance? Photo: Alex Pantling
3. LB: Emil Krafth
Newcastle are out of recognised left-backs unless Paul Dummett returns in time. Could the Sweden international be a makeshift option for the day? Photo: Nathan Stirk
4. RM: Christian Atsu
Has only started a game under Bruce once since September. Might play a key part in what could be a change in formation for United. Photo: Nigel Roddis