Although he has hinted that there may be changes from Sunday’s game, Eddie Howe has insisted that Newcastle will take the Carabao Cup seriously this season.
Howe said: "It's very important. I made that clear in pre-season. I want to see a team that wants to win every game we compete in and every competition is treated with the same importance. I hope that's reflected in our performance tomorrow."
Newcastle will be aiming to avoid a successive defeat at this stage of the competition after being beaten by Burnley on penalties in Round Two last year.
Although they will start the game as heavy-favourites, memories of their defeat to Cambridge United in January will deter any thoughts of overconfidence on Wednesday night.
Here, we take a look at the side Howe may select to face Tranmere Rovers at Prenton Park on Wednesday evening:
Newcastle will be aiming to avoid a successive defeat at this stage of the competition after being beaten by Burnley on penalties in Round Two last year.