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A threadbare Newcastle United head to the capital after a disappointing defeat to Everton in midweek.
The Magpies were beaten 3-0 on Merseyside as Eddie Howe was yet again forced to name the same ten outfield players that had started their previous three matches as injury problems continue to persist.
However, there does seem to be a small chink of light at the end of the tunnel with a few of those injured players seemingly close to a return to the fold, although how quick they are able to do that is unknown.
Ange Postecoglou, meanwhile, also saw his side fall to defeat on Thursday night as he shares a similar headache as his opposite number.
Here, we take a look at the latest injury news from both camps ahead of the clash between Tottenham Hotspur and Newcastle United:
5. Rodrigo Bentancur - out
The Uruguayan was injured on his first start after recovering from an ACL injury. He is expected to miss a couple of months of action. | Getty Images
6. Manor Solomon - out
Solomon had surgery on a knee injury back in October. He is expected to be back in contention in the new year. | AFP via Getty Images
7. Ryan Sessegnon - out
Sessegnon once tore Newcastle United apart during his days with Fulham, but he won’t get an opportunity to repeat that performance this weekend. A thigh injury suffered earlier this campaign will reportedly keep him out for at least another month or so. | AFP via Getty Images
8. Ivan Perisic - out
Perisic suffered an ACL injury and has been ruled-out for the majority of the campaign. | Getty Images