Speaking to Football Insider, Bent says the Frenchman is an integral part of Steve Bruce’s team at United and any long-term absence would prove a ‘humongous blow’ for the Magpies, who occupy 11th in the Premier League table after 16 games.
He said: “A humongous blow – he is key to what they do.
“Him and (Miguel) Almiron, more so him, the way Newcastle play allows him to do what he does which is get up the pitch in a hurry.
“He’s quick, he’s strong, he’s unpredictable so for me, it’s a big blow and Newcastle are going to struggle without him.
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“But hopefully he can come back sooner rather than later.”
Saint-Maximin limped off in the closing stages of Newcastle's 2-1 home win over Southampton at the weekend. Bruce confirmed the £16million winger suffered a hamstring injury.