Action figures and vehicles from popular toy lines including Star Wars, Masters of the Universe, Thundercats, Teenage Ninja Mutant Turtles and MASK will be sold by Vectis Auctions in Stockton on Tuesday, March 9.
Many of the toys are still in their original packaging and the auction is expected to attract a worldwide audience.
One of the items up for sale is a Mattel Masters of the Universe He-Man figure on its original backing card and in great condition which has a pre-sale estimate of £2,500-£3,000.
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A series 1 Skeletor figure also on its backing card is set to go for £2,000-£3,000.
And an unopened Kenner Star Wars vintage Boba Fett figure is set to go for even more at between £3,000 and £5,000.
Still on its original backing card, it is also ‘unpunched’ meaning the toy never found its way onto a toy shop shelf.
Nick Dykes, TV and film specialist at Vectis, said: “The interest we have seen in modern toys, in particular action figures is increasing.
"In particular those from the 1970, 80s and 90s in excellent order have recently recorded four-figure sums for a single piece.”
The toys all come from one anonymous owner who carefully curated the collection buying the best they could find.
Also included in the sale is a Kenner MASK Boulder Hill playset still sealed in its original box with an estimate of £500- £1,000.
A full catalogue for the sale can be viewed online at www.vectis.co.uk