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Newcastle United travel to the Vitality Stadium aiming to banish any demons from their narrow defeat to Borussia Dortmund in midweek - one that left their hopes of qualifying for the Champions League knockout stages hanging by a thread.
The Magpies were dealt another injury blow out in Germany with Callum Wilson being forced off at half-time after suffering a tightness in his hamstring.
Concern over Wilson adds yet another headache for Howe this weekend as he has to deal with a plethora of injuries plus a suspension for Bruno Guimaraes.
The hosts, meanwhile, also have a few problems to deal with ahead of this weekend’s game.
Here, we take a look at the latest injury and team news from both camps ahead of Bournemouth v Newcastle United:
5. Ryan Fredericks - doubt
The 31-year-old is yet to feature for Bournemouth this season but is slowly making his recovery from injury. The game against Newcastle may come slightly too early for him, however, with the most likely return coming after the international break. | Getty Images
6. Tyler Adams - out
Adams has just one Carabao Cup appearance to his name since joining the Cherries from Leeds in the summer. A thigh injury will rule him out of action until the new year. | AFP via Getty Images
7. Sven Botman - out
The Dutchman still has a little longer to go in his recovery from a knee injury. Botman hasn’t featured for the club since the win over Sheffield United last month and will miss the clash against Bournemouth after Howe revealed the defender has suffered a setback in his recovery. | Getty Images
8. Callum Wilson - doubt
Wilson was withdrawn at half-time of the defeat to Borussia Dortmund in midweek and Howe revealed that the striker had felt a tightness in his hamstring. Wilson has been called up by Gareth Southgate to represent England, however, hinting that he may not be out of action for too long. | Getty Images