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Newcastle United travel to the Vitality Stadium aiming to banish any demons from their narrow defeat to Borussia Dortmund in midweek - one that left their hopes of qualifying for the Champions League knockout stages hanging by a thread.
The Magpies were dealt another injury blow out in Germany with Callum Wilson being forced off at half-time after suffering a tightness in his hamstring.
Concern over Wilson adds yet another headache for Howe this weekend as he has to deal with a plethora of injuries plus a suspension for Bruno Guimaraes.
The hosts, meanwhile, also have a few problems to deal with ahead of this weekend’s game.
Here, we take a look at the latest injury and team news from both camps ahead of Bournemouth v Newcastle United:
9. Matt Targett - out
Targett was substituted very early on against Manchester United after suffering a hamstring injury. The left-back has undergone surgery on the injury and will thus miss the next few months of action. | Getty Images
10. Javier Manquillo - out
Howe revealed that Manquillo has been suffering with a groin injury. | AFP via Getty Images
11. Dan Burn - out
Burn injured his lower back against Arsenal and has been ruled-out for a couple of months. | AFP via Getty Images
12. Elliot Anderson - out
Anderson has suffered a back injury and could be sidelined for around eight weeks with the injury. With a very hectic schedule to come, not having Anderson’s services will be a huge blow for the Magpies. | Getty Images