Both teams have their respective injury and suspension worries heading into Sunday’s game. Newcastle will be sweating on the fitness of Joe Willock and hoping that Loris Karius, who has yet to play a game for the Magpies, will be fit enough to start at Wembley.
Manchester United, meanwhile, will be hoping an injury picked up by key man Marcus Rashford, one that saw him substituted against Barcelona with, will not be enough to impact his performance at the weekend.
Here, we take a look at all the selection headaches both camps will have to contend with ahead of Sunday’s game and the latest from Howe and ten Hag:
How big of an impact could these absences have on Sunday’s game? Follow us on our social media channels and let us know your thoughts there.
17. Anthony Gordon
Gordon is cup-tied having featured for Everton in the Carabao Cup before his move to Newcastle United. Photo: Stu Forster
18. Marcus Rashford
Rashford limped off at the end of Manchester United's Europa League clash with Barcelona and posted a photograph of himself with a bandage emoji after the match. Dion Dublin told MUTV: “He was just taking the weight off his left ankle. Maybe he has rocked it a little bit. Hopefully, he can strap it up on Sunday. The medical staff will do what’s right.” Photo: Matthew Peters