A Miguel Almiron brace and goals from Callum Wilson and Sean Longstaff saw Eddie Howe’s side cruise to victory despite Bobby De Cordova-Reid’s late consolation.
Callum Wilson gave Newcastle the lead shortly after Nathaniel Chalobah’s early red card for Fulham.
Miguel Almiron then doubled The Magpies’ advantage in the first half with a stunning volley in the left side of the goal.
Just before the break, Sean Longstaff pounced on a Bernd Leno save from Sven Botman to make it 3-0 to the visitors.
Almiron then grabbed his second of the afternoon after turning in Joe Willock’s cross from close range.
Newcastle looked to be heading towards a 4-0 win when Fulham pulled back a consolation goal in the closing stages through Bobby De Cordova-Reid to make it 4-1.
1. Nick Pope - 6
Had very little to do other than a couple of simple catches. | AFP via Getty Images
2. Kieran Trippier - 8
His delivery from the right caused Fulham problems all afternoon. | Getty Images
3. Fabian Schar - 7
Gave the ball away cheaply on one occasion which almost let Fulham in and blocked an effort from Joe Willock early on but rarely put a foot wrong afterwards. | Getty Images
4. Sven Botman - 8
Saw a header saved in the build up to Newcastle’s third goal. Dealt well with what Fulham threw at him and helped Newcastle dominate from front to back. | Getty Images