But what about the other contenders? Who do the bookies think will go and who do they think will be safe?
Here we take a look at the runners and riders using SkyBet’s Premier League relegation odds.
1. Sheffield United - 5/4
They might have picked up three points on Saturday but the bookies still make Chris Wilder & Co favourites for the drop.
Photo: Shaun Botterill
2. Newcastle United - 5/4
Things are looking grim on Tyneside at present - and that's reflected in the odds. Two losses out of two, one goal and seemingly a million and one problems.
Photo: Marc Atkins
3. Norwich City - 7/4
Daniel Farke's men were rampant against Newcastle on Saturday, scoring three which so easily could have been six or seven. Written off by many, they might just prove people wrong.
Photo: Jordan Mansfield
4. Aston Villa - 2/1
Newly-promoted Villa are one of four teams who have lost their opening two Premier League fixtures.
Photo: Alex Morton