The Reds have been embroiled in the European Super League controversy since last Sunday night, and the Magpies will hope to use the unrest at the club to their advantage and pick up a shock win over Jurgen Klopp's side.
Speaking ahead of Saturday's game, Klopp, when asked whether his side were motivated to kick on after dropping more points earlier in the week with a 1-1 draw against Leeds United, claimed: “Definitely, definitely. You can see the intensity the boys put in (against Leeds) – it’s really there.
“We played a lot of good stuff, we could have played even better in moments, I know that – get a bit more clinical and then we will score goals. Newcastle (is) a different challenge, but we’ll face it.”
A win for the Magpies could see them move as high as 13th in the table, while the Reds could move from seventh to fourth in a tightly-packed top half of the table.
Meanwhile, Newcastle will be starting to assess their transfer targets ahead of the summer window opening, as they look to move on some deadwood and bring in some exciting new talent before the start of next season.
Here are today's biggest transfer stories and the latest team news involving Newcastle United and the rest of the Premier League, as the build-up to the weekend action continues:
9. Willock wants to stay at St James' Park
Newcastle United's hopes of signing star loanee Joe Willock, who could cost north of £20m, look to have received a boost, with reports claiming the player is eager to remain at St James' Park next season. (Football Insider) Photo: Clive Brunskill
10. Reds linked with starlet
Liverpool have been linked with a move for Sparta Prague striker Adam Hlozek, as they plan to overhaul their attacking line this summer. The teenage sensation is also rumoured to be of interest to Arsenal and West Ham. (Football Insider) Photo: VLADIMIR SIMICEK