Fabian Schar and Callum Wilson come into the side for Jamaal Lascelles and the injured Chris Wood.
It’s Wilson’s first start since December 27 and he will lead the side out as captain against the Gunners with Lascelles and Kieran Trippier both on the bench.
Newcastle secured Premier League survival last week and will be looking to end their season on a high in their final two games against Arsenal and Burnley. Tonight’s match will be played in front of a packed St James’s Park crowd for the final time this season.
NUFC line-up to face Arsenal: Dubravka; Krafth, Schar, Burn, Targett; Guimaraes, Longstaff, Joelinton; Almiron, Saint-Maximin, Wilson (C)
Subs: Darlow, Dummett, Lascelles, Ritchie, Trippier, Fernandez, Fraser, Murphy, Gayle
Newcastle have 10 players out in total, here are all of the absentees explained...
9. Jeff Hendrick - ineligible
Has returned from his loan at QPR but is not in Newcastle’s 25 man squad so cannot feature. Photo: Naomi Baker
10. Freddie Woodman - ineligible
Woodman’s loan at AFC Bournemouth has ended following The Cherries’ promotion back to the Premier League. He is ineligible to feature as he is not in Newcastle’s 25 man squad. | Getty Images