Both teams have their respective injury and suspension worries heading into Sunday’s game. Newcastle will be sweating on the fitness of Joe Willock and hoping that Loris Karius, who has yet to play a game for the Magpies, will be fit enough to start at Wembley.
Manchester United, meanwhile, will be hoping an injury picked up by key man Marcus Rashford, one that saw him substituted against Barcelona with, will not be enough to impact his performance at the weekend.
Here, we take a look at all the selection headaches both camps will have to contend with ahead of Sunday’s game and the latest from Howe and ten Hag:
How big of an impact could these absences have on Sunday’s game? Follow us on our social media channels and let us know your thoughts there.
9. Harry Maguire
Maguire missed the game with his old club Leicester City at the weekend, but is expected to be available for selection on Sunday. Ten Hag said: "We still have training to do. I expect to have Maguire and Antony back.” Photo: Alex Caparros
10. Bruno Guimaraes
Like his compatriot Casemiro, Guimaraes has served all three of his three game suspension and will be available to play at Wembley. Photo: Stu Forster
11. Donny Van de Beek
The Dutchman has been ruled-out for the rest of the campaign after sustaining a knee injury. In January, ten Hag said: “Of course, the bad news is he is out for the rest of the season, but the good news is, in the long term, his knee will be OK, and he will be ready to play at the highest levels for the start of pre-season.” Photo: Matthew Peters
12. Nick Pope
Pope is suspended for Sunday’s game after being sent off against Liverpool. The club won’t appeal the decision and so the 30-year-old will have to watch from the stands at Wembley. Howe said: “No, we didn’t appeal,” said Howe. “As much as I felt sorry for Nick, and felt that the red card was really harsh for what he did, abiding by the rules, we didn’t think it worth appealing.” Photo: George Wood